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What causes acne
ACNE
Almost everyone gets acne. Most people have some acne between the ages of 10 to 20.
Almost all teens worry about how their skin looks, but acne is a very common problem that can be well controlled with proper treatment.
Causes of Acne

Acne is caused by an obstruction, or plugging, of the sebaceous follicle (oil gland).
Plugging of the skin opening of the gland causes a blackhead. A plug that occurs below the surface of the skin causes a whitehead. These can become inflamed or infected, which results in small bumps or cysts.
Acne is not caused by foods, or by poor hygiene, as is commonly believed. Excessive face washing or scrubbing with abrasive pads can actually make acne worse!
What causes acne

What causes acne

What causes acne
ACNE
Almost everyone gets acne. Most people have some acne between the ages of 10 to 20.
Almost all teens worry about how their skin looks, but acne is a very common problem that can be well controlled with proper treatment.
Causes of Acne

Acne is caused by an obstruction, or plugging, of the sebaceous follicle (oil gland).
Plugging of the skin opening of the gland causes a blackhead. A plug that occurs below the surface of the skin causes a whitehead. These can become inflamed or infected, which results in small bumps or cysts.
Acne is not caused by foods, or by poor hygiene, as is commonly believed. Excessive face washing or scrubbing with abrasive pads can actually make acne worse!
What causes acne

Develop a Written Asthma Management Plan
As part of the overall management of patients with asthma, the health-care provider, in consultation with the patient or the parent or guardian of a child with asthma, should develop a written plan as part of educating patients regarding self management, especially for patients with moderate or severe persistent asthma and those with a history of severe exacerbation.
The National Heart, Lung, and Blood Institute provides more specific advice on asthma management plans, emphasizing the provider/patient partnership (available at http://www.
nhlbi.nih.gov/health/public/lung/asthma/asthma.htm#plan).
Writing the management plan helps clarify expectations for treatment (Box 4) and provides patients with an easy reference for remembering how to manage their asthma. The action plan should include written instructions on recognizing symptoms and signs of worsening asthma; taking appropriate medicines (type, dose, and frequency); recognizing when to seek medical care; and monitoring response to medications.
Symptom-based plans may be equally effective as plans based
on peak flow monitoring, although some patient preferences and circumstances (e.g., inability to recognize or report signs and symptoms of worsening asthma) may warrant a choice of peak flow monitoring. The management plan should be reviewed and adjusted, as needed, at every visit. For children, a copy of the plan should be given to each care giver and the child’s school.
Develop a Written Asthma Management Plan


Develop a Written Asthma Management Plan

Develop a Written Asthma Management Plan
As part of the overall management of patients with asthma, the health-care provider, in consultation with the patient or the parent or guardian of a child with asthma, should develop a written plan as part of educating patients regarding self management, especially for patients with moderate or severe persistent asthma and those with a history of severe exacerbation.
The National Heart, Lung, and Blood Institute provides more specific advice on asthma management plans, emphasizing the provider/patient partnership (available at http://www.
nhlbi.nih.gov/health/public/lung/asthma/asthma.htm#plan).
Writing the management plan helps clarify expectations for treatment (Box 4) and provides patients with an easy reference for remembering how to manage their asthma. The action plan should include written instructions on recognizing symptoms and signs of worsening asthma; taking appropriate medicines (type, dose, and frequency); recognizing when to seek medical care; and monitoring response to medications.
Symptom-based plans may be equally effective as plans based
on peak flow monitoring, although some patient preferences and circumstances (e.g., inability to recognize or report signs and symptoms of worsening asthma) may warrant a choice of peak flow monitoring. The management plan should be reviewed and adjusted, as needed, at every visit. For children, a copy of the plan should be given to each care giver and the child’s school.
Develop a Written Asthma Management Plan



Classify Severity of Asthma
Because asthma is characterized by varying signs and symptoms, for appropriate treatment and monitoring, the severity of such signs and symptoms must be classified at the initial and all subsequent visits. Initially and before treatment has been optimized, clinical signs, symptoms, and peak flow monitoring or spirometry are used to classify severity (Table 2)
(Box 2). After the patient’s asthma is stable, severity is subsequently classified according to the level of medication required to maintain treatment goals.
Health-care providers should have the knowledge, equipment, staff or access to needed resources to aid in classification and proper management of all patients with asthma.
Classify Severity of Asthma

Classify Severity of Asthma

Classify Severity of Asthma
Because asthma is characterized by varying signs and symptoms, for appropriate treatment and monitoring, the severity of such signs and symptoms must be classified at the initial and all subsequent visits. Initially and before treatment has been optimized, clinical signs, symptoms, and peak flow monitoring or spirometry are used to classify severity (Table 2)
(Box 2). After the patient’s asthma is stable, severity is subsequently classified according to the level of medication required to maintain treatment goals.
Health-care providers should have the knowledge, equipment, staff or access to needed resources to aid in classification and proper management of all patients with asthma.
Classify Severity of Asthma

how get rid of acne - ways to get rid of acne
way how to get rid of acne fast&pimples overnight
10 methods to obtain Rid of acne breakouts at Home
If you have acne, but you are fortunate in that it is mild or occasional, you possess the option of successfully stopping and treating acne breakouts at home. understanding how to obtain rid of acne utilizing home-based techniques is safe, effective, and inexpensive. numerous of those methods do not price you something at all, as they are merely methods to modify your behaviors and wellbeing habits. for individuals who wish to obtain a far better knowing of how to obtain rid of acne, there are numerous methods by which to make an try to do it.
First, understanding how to obtain rid of acne breakouts suggests understanding easy methods to carry great treatment of your skin, regardless of whether or not you have acne breakouts or not. whilst acne breakouts is frustrating, resist the temptation to make an try to do something that may irritate your skin. rather than washing your confront with ordinary cleaning soap along with a hard washcloth, use your fingertips along with a mild cleanser formulated for acne breakouts prone skin.
how get rid of acne - ways to get rid of acne
Furthermore, knowing how to obtain rid of acne breakouts most successfully will depend upon whether your skin tone is oily, or whether or not it is dried out or sensitive. If your skin tone is oily, you will most probable wish to use a water-based, alcohol-free, non-comedogenic cleanser. If your skin is dried out or sensitive, you will wish to use a medicated moisturizer following washing your face. this can soothe your skin tone if it gets red-colored or irritated.
While it may possibly not be obvious, limiting your sunshine coverage is an additional method to avoid acne breakouts outbreaks. additionally to becoming an excellent method to avoid skin tone cancer, staying out with the sunshine is an excellent method to avoid acne breakouts as well. numerous men and women maintain the misconception that sunshine exposure can avoid and deal with acne, but this really is not the case.
Knowing how to obtain rid of acne breakouts by adhering to some sensible skin tone treatment program will not do you any great for individuals who do not maintain your arms away of your face. Do not make an effort to get rid of pimples by picking at them or popping them, and do not make an effort to get rid of blackheads or whiteheads by squeezing them. It is not suggested that you just use any instruments to remove blackheads or whiteheads, either. Finally, maintain aside from resting your chin or the aspect of your confront in your hands.
ways to get rid of acne - how to get get rid of acne

In addition, you will not wish to undo the results of the sensible skin tone treatment program by sleeping on sheets and pillowcases which have not been washed regularly. Oils out of your face and system can create up on towels, clothing, and bed sheets, and will possess the impact of clogging your pores.
You may possibly wish to learn how to obtain rid of acne breakouts with over-the-counter medications.
Fortunately, over-the-counter drugs are simple to find, as they are usually available at your regional medicine shop or supermarket plus they are fairly inexpensive.
of one of the most typical elements in this type of drugs is benzoyl peroxide. To begin, you may wish to think about utilizing an over-the-counter item using a minimal concentration of benzoyl peroxide, that include 2.5% or 5%. If this does not function in inclusion to you would like, you may possibly wish to think about a item using a greater concentration, that include 10%.
If you are curious about how to obtain rid of acne breakouts utilizing ingredients other than over-the-counter medications, you may possibly come across what you choose within your refrigerator, cupboard, or
medicine cabinet. Some folk treatments for treating acne breakouts consist of placing little quantities of toothpaste in your pimples, rubbing your confront with lemon or lime juice, or creating a
mask from cooked oatmeal.
Fortunately, understanding how to obtain rid of acne breakouts is not difficult. It merely needs a little of adjustment for your everyday routine, in inclusion to becoming conscious of and eliminating any poor routines
you have that contribute to acne breakouts outbreaks.
How to get rid of acne permanently - ways to get rid of acne scars

how get rid of acne - ways to get rid of acne

how get rid of acne - ways to get rid of acne
way how to get rid of acne fast&pimples overnight
10 methods to obtain Rid of acne breakouts at Home
If you have acne, but you are fortunate in that it is mild or occasional, you possess the option of successfully stopping and treating acne breakouts at home. understanding how to obtain rid of acne utilizing home-based techniques is safe, effective, and inexpensive. numerous of those methods do not price you something at all, as they are merely methods to modify your behaviors and wellbeing habits. for individuals who wish to obtain a far better knowing of how to obtain rid of acne, there are numerous methods by which to make an try to do it.
First, understanding how to obtain rid of acne breakouts suggests understanding easy methods to carry great treatment of your skin, regardless of whether or not you have acne breakouts or not. whilst acne breakouts is frustrating, resist the temptation to make an try to do something that may irritate your skin. rather than washing your confront with ordinary cleaning soap along with a hard washcloth, use your fingertips along with a mild cleanser formulated for acne breakouts prone skin.
how get rid of acne - ways to get rid of acne
Furthermore, knowing how to obtain rid of acne breakouts most successfully will depend upon whether your skin tone is oily, or whether or not it is dried out or sensitive. If your skin tone is oily, you will most probable wish to use a water-based, alcohol-free, non-comedogenic cleanser. If your skin is dried out or sensitive, you will wish to use a medicated moisturizer following washing your face. this can soothe your skin tone if it gets red-colored or irritated.
While it may possibly not be obvious, limiting your sunshine coverage is an additional method to avoid acne breakouts outbreaks. additionally to becoming an excellent method to avoid skin tone cancer, staying out with the sunshine is an excellent method to avoid acne breakouts as well. numerous men and women maintain the misconception that sunshine exposure can avoid and deal with acne, but this really is not the case.
Knowing how to obtain rid of acne breakouts by adhering to some sensible skin tone treatment program will not do you any great for individuals who do not maintain your arms away of your face. Do not make an effort to get rid of pimples by picking at them or popping them, and do not make an effort to get rid of blackheads or whiteheads by squeezing them. It is not suggested that you just use any instruments to remove blackheads or whiteheads, either. Finally, maintain aside from resting your chin or the aspect of your confront in your hands.
ways to get rid of acne - how to get get rid of acne

In addition, you will not wish to undo the results of the sensible skin tone treatment program by sleeping on sheets and pillowcases which have not been washed regularly. Oils out of your face and system can create up on towels, clothing, and bed sheets, and will possess the impact of clogging your pores.
You may possibly wish to learn how to obtain rid of acne breakouts with over-the-counter medications.
Fortunately, over-the-counter drugs are simple to find, as they are usually available at your regional medicine shop or supermarket plus they are fairly inexpensive.
of one of the most typical elements in this type of drugs is benzoyl peroxide. To begin, you may wish to think about utilizing an over-the-counter item using a minimal concentration of benzoyl peroxide, that include 2.5% or 5%. If this does not function in inclusion to you would like, you may possibly wish to think about a item using a greater concentration, that include 10%.
If you are curious about how to obtain rid of acne breakouts utilizing ingredients other than over-the-counter medications, you may possibly come across what you choose within your refrigerator, cupboard, or
medicine cabinet. Some folk treatments for treating acne breakouts consist of placing little quantities of toothpaste in your pimples, rubbing your confront with lemon or lime juice, or creating a
mask from cooked oatmeal.
Fortunately, understanding how to obtain rid of acne breakouts is not difficult. It merely needs a little of adjustment for your everyday routine, in inclusion to becoming conscious of and eliminating any poor routines
you have that contribute to acne breakouts outbreaks.
How to get rid of acne permanently - ways to get rid of acne scars

Donating bone marrow stem cells
There are two ways of collecting stem cells from donors for a transplant:
• peripheral blood stem cell (PBSC) harvest: where donor stem cells are collected from the circulating blood using a process called leukapheresis (see below)
• bone marrow harvest: where bone marrow is collected from bone while the donor is under general anaesthetic.
Most transplants from related donors use PBSC, while transplants from unrelated donors use either PBSC or bone marrow harvest depending on a number of factors, including the patient’s disease and donor preference.
Collecting peripheral blood stem cells
Many donors prefer this method because they don’t need an anaesthetic and won’t have pain after it is done. They need to be injected with a drug called granulocyte colony stimulating factor (G-CSF) for a few days before the procedure, which may have some temporary side effects.
Pre-treatment with G-CSF
The transplant team will prescribe G-CSF. The donor takes it home, and has it injected under the skin once or twice a day for about four days before stem cells are collected on the fifth, and occasionally the sixth day. Some donors choose to inject themselves, but others have someone else – a relative, a nurse or their local doctor – inject the drug.
G-CSF is a synthetic copy of a naturally occurring bone marrow hormone. The hormone is not usually detectable in the body, but the immune system makes it in response to infection. Its natural action is to stimulate the growth of bone marrow stem cells, which can become white cells to fight infection. It also causes the release of stem cells from the marrow into the blood. When enough G-CSF is given, large numbers of stem cells are released into the blood, which can be collected for the transplant.
Side effects
Most donors experience some side effects from G-CSF. These are mostly flu-like symptoms, such as aches and pains, fatigue and generally feeling a “bit off.” The symptoms usually are mild and controlled by paracetamol, but occasionally donors can feel more unwell and need stronger painkillers.
Severe side effects are rare but there have been rare reports of a ruptured spleen in donors, as G-CSF enlarges the spleen (a large organ under the left side of the rib cage). However, many thousands of normal donors have been treated with G-CSF without any serious short- or long-term side effects.
Donating bone marrow stem cells
Harvesting the cells – leukapheresis
On the day of collection, the donor is attached to a machine that collects or ‘harvests’ stem cells from the blood. The collection process, which is called leukapheresis, is usually done at the transplant centre if the donor is related, but always at another collection centre if the donor is unrelated, on an outpatient basis over 3-6 hours.
The donor is awake throughout the procedure. At the beginning, a needle is put into a large vein in the crook of each elbow, and connected by tubes to the apheresis machine. This is basically a big centrifuge, which spins the blood and separates it into white blood cells, red cells and plasma.
The blood is withdrawn from one arm of the donor, passed through the machine, and the portion of the white blood cells that includes the stem cells are collected – a bit like skimming cream off milk. The rest of the blood is then returned to the donor through the other arm. About 12L of blood is processed through the machine.
The donor usually notices no side effects, but occasionally changes in the calcium level in the blood, caused by the anticoagulant solution (citrate) used to stop the blood clotting in the machine, may cause a tingling feeling. Calcium treatment will reverse this. More rarely, donors can feel faint during the procedure because of low blood pressure. The collection will be stopped if this happens.
Some donors don’t have accessible veins in their arms and may need to have the needle put into a large vein in the groin. The insertion of this needle is less pleasant and has a greater risk of bruising, so is only used if there is no alternative.
Most donors can go home within a few hours of the collection. The side effects of G-CSF usually go away within a few days of the drug being stopped.
Most donor leukapheresis procedures collect enough stem cells for a successful transplant. The cells are collected in a bag, usually in a volume of 150-200mL, and the stem cells are counted in the laboratory. About one in three donors will need to have a second collection the next day, after another dose or two of G-CSF.
Donating bone marrow stem cells
Bone marrow harvest
A bone marrow harvest is done in a hospital operating room, usually under general anaesthesia. It is a low-risk procedure, but the donor will feel sore afterwards. While the donor is under anaesthesia, a needle is put inside the rear hipbone (the iliac crest), which contains a lot of bone marrow.
The bone marrow is a thick, red liquid and is extracted with needles and syringes. Several skin punctures on each hip and multiple bone punctures are usually needed to extract the required amount of bone marrow. No surgical cuts or stitches are involved – only skin punctures where the needle was inserted.
The amount of bone marrow harvested depends on the size of the patient. Usually 1L of marrow and blood is harvested. Although this may sound like a lot, it is only about 2% of a person’s bone marrow and the body replaces it in four weeks.
When the anaesthesia wears off, the donor will feel some discomfort at the harvest site, as if they have had a hard fall. It can usually be relieved with paracetamol. There may be some colourful bruising at the back of the hips in the week after the harvest.
Donors can usually go home after an overnight stay in hospital and can resume their normal activities in a few days. Regular blood donors will probably need to wait a while before giving blood, at least until they have their haemoglobin level checked after the harvest.
Sometimes the bone marrow may be treated to remove T cells (T cell depletion) to reduce the risk of graft-versus-host disease.
Donating bone marrow stem cells
Key points
• Most transplants from related donors use stem cells collected from the circulating blood using a process called leukapheresis.
• Most transplants from unrelated donors use bone marrow cells, which are collected from bone while the donor is under general anaesthetic.
• Before the harvest donors will be injected with a drug called G-CSF, which stimulates bone marrow stem cells to grow and multiply.
• G-CSF often causes mild side effects, such as flu-like symptoms. The side effects of G-CSF usually go away within a few days of the drug being stopped. Severe side effects are rare.
• Leukapheresis is a relatively painless procedure. Almost all donors can go home within a few hours of it being done.
• Bone marrow harvest is done in a hospital operating room, usually under general anaesthesia. It is a low-risk procedure, but the donor will feel sore afterwards.
Donating bone marrow stem cells

Donating bone marrow stem cells

Donating bone marrow stem cells
There are two ways of collecting stem cells from donors for a transplant:
• peripheral blood stem cell (PBSC) harvest: where donor stem cells are collected from the circulating blood using a process called leukapheresis (see below)
• bone marrow harvest: where bone marrow is collected from bone while the donor is under general anaesthetic.
Most transplants from related donors use PBSC, while transplants from unrelated donors use either PBSC or bone marrow harvest depending on a number of factors, including the patient’s disease and donor preference.
Collecting peripheral blood stem cells
Many donors prefer this method because they don’t need an anaesthetic and won’t have pain after it is done. They need to be injected with a drug called granulocyte colony stimulating factor (G-CSF) for a few days before the procedure, which may have some temporary side effects.
Pre-treatment with G-CSF
The transplant team will prescribe G-CSF. The donor takes it home, and has it injected under the skin once or twice a day for about four days before stem cells are collected on the fifth, and occasionally the sixth day. Some donors choose to inject themselves, but others have someone else – a relative, a nurse or their local doctor – inject the drug.
G-CSF is a synthetic copy of a naturally occurring bone marrow hormone. The hormone is not usually detectable in the body, but the immune system makes it in response to infection. Its natural action is to stimulate the growth of bone marrow stem cells, which can become white cells to fight infection. It also causes the release of stem cells from the marrow into the blood. When enough G-CSF is given, large numbers of stem cells are released into the blood, which can be collected for the transplant.
Side effects
Most donors experience some side effects from G-CSF. These are mostly flu-like symptoms, such as aches and pains, fatigue and generally feeling a “bit off.” The symptoms usually are mild and controlled by paracetamol, but occasionally donors can feel more unwell and need stronger painkillers.
Severe side effects are rare but there have been rare reports of a ruptured spleen in donors, as G-CSF enlarges the spleen (a large organ under the left side of the rib cage). However, many thousands of normal donors have been treated with G-CSF without any serious short- or long-term side effects.
Donating bone marrow stem cells
Harvesting the cells – leukapheresis
On the day of collection, the donor is attached to a machine that collects or ‘harvests’ stem cells from the blood. The collection process, which is called leukapheresis, is usually done at the transplant centre if the donor is related, but always at another collection centre if the donor is unrelated, on an outpatient basis over 3-6 hours.
The donor is awake throughout the procedure. At the beginning, a needle is put into a large vein in the crook of each elbow, and connected by tubes to the apheresis machine. This is basically a big centrifuge, which spins the blood and separates it into white blood cells, red cells and plasma.
The blood is withdrawn from one arm of the donor, passed through the machine, and the portion of the white blood cells that includes the stem cells are collected – a bit like skimming cream off milk. The rest of the blood is then returned to the donor through the other arm. About 12L of blood is processed through the machine.
The donor usually notices no side effects, but occasionally changes in the calcium level in the blood, caused by the anticoagulant solution (citrate) used to stop the blood clotting in the machine, may cause a tingling feeling. Calcium treatment will reverse this. More rarely, donors can feel faint during the procedure because of low blood pressure. The collection will be stopped if this happens.
Some donors don’t have accessible veins in their arms and may need to have the needle put into a large vein in the groin. The insertion of this needle is less pleasant and has a greater risk of bruising, so is only used if there is no alternative.
Most donors can go home within a few hours of the collection. The side effects of G-CSF usually go away within a few days of the drug being stopped.
Most donor leukapheresis procedures collect enough stem cells for a successful transplant. The cells are collected in a bag, usually in a volume of 150-200mL, and the stem cells are counted in the laboratory. About one in three donors will need to have a second collection the next day, after another dose or two of G-CSF.
Donating bone marrow stem cells
Bone marrow harvest
A bone marrow harvest is done in a hospital operating room, usually under general anaesthesia. It is a low-risk procedure, but the donor will feel sore afterwards. While the donor is under anaesthesia, a needle is put inside the rear hipbone (the iliac crest), which contains a lot of bone marrow.
The bone marrow is a thick, red liquid and is extracted with needles and syringes. Several skin punctures on each hip and multiple bone punctures are usually needed to extract the required amount of bone marrow. No surgical cuts or stitches are involved – only skin punctures where the needle was inserted.
The amount of bone marrow harvested depends on the size of the patient. Usually 1L of marrow and blood is harvested. Although this may sound like a lot, it is only about 2% of a person’s bone marrow and the body replaces it in four weeks.
When the anaesthesia wears off, the donor will feel some discomfort at the harvest site, as if they have had a hard fall. It can usually be relieved with paracetamol. There may be some colourful bruising at the back of the hips in the week after the harvest.
Donors can usually go home after an overnight stay in hospital and can resume their normal activities in a few days. Regular blood donors will probably need to wait a while before giving blood, at least until they have their haemoglobin level checked after the harvest.
Sometimes the bone marrow may be treated to remove T cells (T cell depletion) to reduce the risk of graft-versus-host disease.
Donating bone marrow stem cells
Key points
• Most transplants from related donors use stem cells collected from the circulating blood using a process called leukapheresis.
• Most transplants from unrelated donors use bone marrow cells, which are collected from bone while the donor is under general anaesthetic.
• Before the harvest donors will be injected with a drug called G-CSF, which stimulates bone marrow stem cells to grow and multiply.
• G-CSF often causes mild side effects, such as flu-like symptoms. The side effects of G-CSF usually go away within a few days of the drug being stopped. Severe side effects are rare.
• Leukapheresis is a relatively painless procedure. Almost all donors can go home within a few hours of it being done.
• Bone marrow harvest is done in a hospital operating room, usually under general anaesthesia. It is a low-risk procedure, but the donor will feel sore afterwards.
Donating bone marrow stem cells

The basics of bone marrow transplants
A bone marrow transplant (BMT) is a fairly new treatment for diseases that until recently could not be cured. Since it was first used with good results in 1968, this treatment has been used for patients with immune system diseases and blood diseases such as leukaemia, lymphoma and multiple myeloma.
In Australia each year, around 1,000 children and adults have a BMT. More than 300 people have a BMT each year in New South Wales.
What is bone marrow?
Bone marrow is the soft, spongy part in the centre of your bones where blood cells are produced. The bone marrow makes stem cells, which are early-stage cells that produce other cells. Each tissue in the body contains stem cells that renew and replace that tissue when needed due to damage or wear and tear. Stem cells generate all blood cells in the human body, including red cells, white cells and platelets.
Types of BMT
Allogeneic transplant
This type of transplant uses stem cells donated by another person (a donor) and is the focus of this book. It is called a syngeneic transplant if the donor is an identical twin.
The two types of allogeneic transplants are:
• Myeloablative or full allo: the aim is to destroy the patient’s marrow and kill the cancer cells.
• Non-myeloablative (“mini” allo): the aim is to suppress the patient’s marrow and allow the donor cells to grow and attack the cancer cells. This is the graft-versus-tumour effect.
There are two ways to collect or harvest the donor’s stem cells:
�� A peripheral blood stem cell harvest: this is used for most adult transplants and collects stem cells from the donor’s circulating blood.
�� A bone marrow harvest: this collects stem cells from the donor’s bone marrow, usually from the hip bones.
The donor’s stem cells must match the genetic make-up of your own cells as closely as possible. Blood tests, called tissue typing, are done to work out if the donor’s cells match.
The most suitable donor is usually a brother or sister whose bone marrow is a close match. There is a 25-35% chance that a patient will have a family member whose stem cells match. But if no matching relative can be found, an unrelated donor may be found in the Australasian/International Bone Marrow Donor Registry. A mismatched or autologous BMT may also be considered.
The basics of bone marrow transplants
The basics of bone marrow transplants
Autologous transplant
An autologous transplant uses your own stem cells. This type of transplant can be done if the disease is in remission or if the illness does not involve the bone marrow (eg, Hodgkin’s disease, non-Hodgkin’s lymphoma).
For an autologous BMT, stem cells are taken from the patient’s blood before the transplant, stored and then given back after high-dose chemotherapy or radiotherapy.
This book does not describe autologous BMT in detail. For more information about autologous transplants, see the BMT Network NSW publication, Autologous Bone Marrow Transplant: A Patient’s Guide.
Preparing for a BMT
The BMT team
An expert team of doctors, nurses and other support staff will care for you. The team can quickly identify and treat any problems or side effects. A good BMT program will also give patients and their families emotional and psychological support before, during and after the transplant.
For a BMT to work well, you must be healthy enough to cope with the procedure. When deciding if you should have a BMT, your doctor will consider your age, general physical condition and the type and stage of your disease.
The work up
Before a BMT, a number of tests are carried out to ensure you are healthy enough for the treatment. You will also have tests of heart, lung and kidney function before and after the BMT so your doctor can check whether these organs are still working as well after the transplant. The pre-BMT tests (also called the work up) are usually done before you are in hospital, but may be done after you are admitted.
You will need to have a dental check-up and all necessary work done before the BMT. If you or your dentist is unsure, please check with your BMT team before any work is started.
The basics of bone marrow transplants
Making informed decisions
Long-term implications
It is important to think about some of the possible long-term effects, such as infertility, and discuss them with your transplant doctor before starting a BMT. See page ?? for more information.
Gathering information
When you are considering a BMT, you will be given a lot of information about the process. Some people do in-depth research and think through every detail, while others just want enough information for the next day or stage. Some people only want to know enough to be informed, and choose not to read or listen to anything negative so they can stay motivated and focused.
A BMT is a serious and complicated procedure so it is vital you are informed and that you clearly understand what the BMT means for you. This requires good communication with your BMT doctor and the rest of the team.
At your first visits to the doctor, you will receive a lot of information about the proposed BMT, its side effects and possible complications. To help you absorb this information, it can help to take notes during the consultation or tape-record the discussion. Many people like to have a relative or friend go with them, to take part in the discussion, take notes or just listen.
If you don’t understand what you’ve been told, don’t be afraid to ask questions or to ask for the information to be repeated as often as you need. Questions are a good sign that you are working in partnership with your medical team. It is very important to be involved in your care and to express your concerns before, during and after a BMT. Your role is crucial, particularly in telling the team about how you are feeling and any symptoms you are having.
In the days before the BMT, you will need to sign a number of consent forms for the treatment or clinical trial.
Finally, remember that not everyone will want to go ahead with a BMT. After thinking about all the possible risks and benefits, some people decide it is not for them. In this case, you need to tell your doctors, and talk to them about other treatments. Your doctor will still give you the best other treatment options available.
How is a BMT done?
Collecting bone marrow stem cells
The stem cells are collected from the donor’s blood or bone marrow. If the donor is related to you, the stem cells will usually be collected from the blood. Cells from unrelated donors are harvested from the either the peripheral blood or the bone marrow, under general anaesthetic, depending on what your doctor believes is best for you and/or donor preference.
The central line
If you don’t already have one, a central venous catheter will be inserted under the skin of your chest into a vein. It is also called a central line or Hickman catheter depending on the type of line.
A central line is a long, hollow tube that usually has two or three passages (called lumens) to allow for a number of uses. It is made of silicone or hard plastic. Your central line will stay in place during the BMT and may be used to collect blood samples and to give you all the medications and fluids you need.
Your central line will usually be inserted into a large vein that runs beneath your collar bone with the tip sitting near to the entry into your heart. The rest of the central line remains outside your body for easy access. A clamp keeps the tube closed when it is not being used. The central line may be put in when you are in the operating theatre, in the x-ray department or on the ward.
Add diagram showing central line in place
Conditioning treatment
You will have several days of chemotherapy and/or radiotherapy, which destroy bone marrow and cancerous cells and make room for the healthy stem cells. This is called the conditioning or preparative regimen.
You may also hear the phrase ‘countdown to transplant’, because this treatment is expressed in your medical notes in terms of the number of days until the transplant. For example, day -5 (minus 5) means that you are five days away from the transplant day, which is called day 0. The type and number of days of chemotherapy and/or radiotherapy vary according to the disease being treated and the protocol or preferred treatment plan of the hospital where the BMT is being done.
For a myeloablative BMT, the dose of chemotherapy and/or radiotherapy given to patients during conditioning is much stronger than doses given to patients with the same disease who are not having a BMT. You may become weak, irritable and nauseous. Anti-nausea medications will help during this period. Don’t be alarmed if your blood results go down at this time, as this is what the chemotherapy or radiotherapy is supposed to do – that is, empty your bone marrow before your transplant.
The transplant
The transplant will take place a day or two after the chemotherapy and/or radiotherapy. The transplant is not a surgical procedure. It takes place in your hospital room, not an operating room.
You may be given medication before the transplant to prevent a reaction to the transplanted cells. This is more likely to occur when the match between the donor marrow and the patient is not exact or the blood groups are different.
The healthy bone marrow stem cells are infused through your central line, in much the same way that any blood product is given. Many patients describe the actual transplant as an anticlimax, as it all over so quickly – usually between 30 minutes and an hour.
You will be checked frequently for signs of fever, chills, hives and chest pains while the bone marrow is being infused. When the transplant is completed, the days and weeks of waiting begin.
The bone marrow begins to grow (engraftment)
Engraftment means new cell growth. It takes place after your bone marrow transplant when there is a sustained rise in new blood cell production. As a general guide, engraftment is said to have happened once the white blood cell count rises above 0.5 x 10 9 /L and the platelet count to above 20 x 103 /L without transfusion.
The 2-4 weeks after the transplant are the most critical. The high-dose chemotherapy and/or radiotherapy given to you during conditioning destroyed your bone marrow, crippling your immune or defence system, leaving your body with no natural defences against infection.
As you wait for the transplanted bone marrow to migrate to the cavities of the large bones, engraft and begin producing normal blood cells, you will be very susceptible to infection and excessive bleeding. You will be given multiple antibiotics and blood transfusions to help prevent and fight infection. You will also have transfusions of platelets to prevent bleeding and additional medications to prevent and control graft-versus-host disease (GVHD), which happens when the white blood cells from the donor marrow attack the cells of the patient’s body. (For detailed information of GVHD, see page?)
While many infections start from within the body, your BMT team will take a number of precautions to minimise your exposure to viruses and bacteria in your environment. These will vary from centre to centre. Visitors and hospital personnel will wash their hands with antiseptic soap and may wear protective gowns, gloves and/or masks while in your room.
Any visitors or relatives will be asked not to visit if they are unwell eg, if they have a sore throat, runny nose, a cold /flu or upset stomach. Fresh fruits, vegetables, plants and cut flowers, which often carry fungi and bacteria that pose a risk of infection, may not be allowed in your room.
When leaving the room, you may wear a mask, gown and gloves as a barrier against bacteria and virus, and also to remind others that you are susceptible to infection.
Blood samples will be taken daily to monitor engraftment and organ function. When the transplanted bone marrow engrafts and begins producing normal blood cells, you will gradually be taken off the antibiotics, and blood and platelet transfusions will generally no longer be required.
Once the bone marrow is producing a sufficient number of healthy red blood cells, white blood cells and platelets, you will be discharged from the hospital, provided no other complications have developed. BMT patients typically spend 4-8 weeks in hospital.
How you may feel physically during the transplant
A BMT is a physically, emotionally and psychologically taxing procedure for you and your family. Seek as much help as you need to cope – toughing it out on your own is not usually the best way to cope with the transplant experience.
At times, you may feel very sick and weak during the transplant. Walking, sitting up in bed for long periods of time, reading books, talking on the phone, visiting with friends or even watching TV may require more energy than you have.
Complications can develop after a bone marrow transplant such as infection, bleeding, GVHD or liver disease, which can create additional discomfort (see page?). Pain is usually controlled with medication, which may include the use of intravenous morphine or other narcotic drugs. In addition, mouth and throat sores can develop that make eating and swallowing uncomfortable and difficult. Temporary mental confusion sometimes occurs and can be frightening for the patient who may not realise it is only temporary. The medical and nursing staff will help you and your carers deal with these problems.
Dealing with emotional and psychological concerns
Being diagnosed with a life-threatening illness can be a traumatic experience. It is common to feel overwhelmed by the amount of information you receive and the need for urgent treatment. Each person feels differently and responds differently. People will find some aspects of the treatment process more stressful than others.
It is important you know that BMT is a team effort and that you are the central and most important person in this team. Understanding your treatment plan and clear communication are essential elements in maintaining your emotional and psychological well-being. People often say it is the unexpected symptom, complication and treatment that upsets or frightens them the most. A BMT already involves a degree of uncertainty. Poor communication can add unnecessary stress to this situation. Don’t hesitate to clarify any aspect of the process.
People will vary in the amount of information they want about the transplant. Some will want to speak to others who have been through a bone marrow transplant. Some will want to be well researched on all aspects of the transplant process. Others will only need to have minimal facts about their proposed treatment. Whichever category you fall into, it will be important for you to have all the information you need about your treatment before the transplant.
You may find that you feel isolated with little control over your day-to-day activity because of the precautions taken to guard against infection while your immune system is not working properly. You will be in a single room and the number of visitors you can have at one time is restricted.
Make your room your own space with your personal effects. Try to stay as independent as you can and talk to your nurses about how you can participate in your care. Lack of privacy is another common issue for people having a BMT – talk to your nurse about allocating times when you will be as undisturbed as possible.
Waiting for the transplanted stem cells to engraft, for blood counts to return to safe levels or for side effects to disappear can be very frustrating and lead to increased stress. Try to remain positive and be realistic in your goals. BMT is an individual process that cannot be predicted all of the time.
You may find that personal relationships with family and friends come under pressure during BMT. This is not uncommon. Relationships within families will change, and it is important to recognise what these changes will be. Talk to the BMT social worker if you need help.
Each family member or close friend will cope with your BMT in their own way and this may, at times, lead to misunderstandings or conflict. Just because a family member or friend is not visiting does not mean they don’t care – they may just be taking some time out as their way of coping.
Psychological discomfort, like physical discomfort, is a normal symptom of the BMT experience. Social workers and psychologists/psychiatrists are also part of your BMT team, so call on them when you need help. There is no right or wrong way to manage all the challenges and stresses that BMT throws at you. There is only the method that works for you.
Going home
Recovering from a BMT continues for some months after you leave hospital. For the first few weeks you may be too weak to do much more than sleep, sit up and walk a bit around the house. You will need to visit the hospital or clinic regularly so your BMT team can monitor your progress and administer any medications and/or blood products needed.
It will take at least six months before you will be ready to return to work or your normal daily activities. You’ll need lots of patience and determination to cope during this period. Some people find that reaching their ‘new normal’ takes longer than others.
Your new marrow is still in its infancy and is not yet able to protect you from some bacteria and viruses encountered in everyday life. The medications you will need to control GVHD only add to this. So it is important to protect yourself from potential sources of infection. Enjoy the outdoors, dine alfresco, keep sick friends and relatives away, see movies and do the shopping at quiet times. You can get back to a normal life; you just have to take a little extra care.
Life after BMT
Life after transplant can be both exhilarating and stressful. On the one hand, it is exciting to be alive after being so close to death, and many people find their quality of life has improved after transplant.
But there is always the worry that a relapse will occur. Also, innocent statements or events can sometimes conjure up unpleasant memories of the transplant experience long after recovery. It can take a long time to come to grips with these difficulties. Tell your BMT team about any difficulties you experience.
Shaded box
Frequently asked questions
What is a bone marrow transplant (BMT)?
A BMT is a standard treatment option for some people who have life-threatening blood or immune system diseases. It is the process of replacing unhealthy bone marrow cells (stem cells) with healthy bone marrow cells. The healthy bone marrow cells are re-infused intravenously after very strong chemotherapy and/or radiotherapy, which kills your unhealthy bone marrow cells. The re-infusion of healthy bone marrow cells essentially rescues you from your chemotherapy and/or radiation by enabling your bone marrow to start producing new red and white blood cells and platelets.
What is the difference between a BMT and a peripheral blood stem cell transplant?
Both transplants aim to do the same thing – replace bone marrow stem cells in a person who has had their bone marrow destroyed by large doses of chemotherapy and or radiotherapy.
Bone marrow is the spongy substance found in the hollow of bones of the hips, legs and arms. It contains stem cells (also called CD34s), which produce all circulating blood cells: red blood cells, white blood cells and platelets.
When the stem cells are collected from circulating blood, the transplant is called a peripheral blood stem cell transplant. A transplant with stem cells collected from the marrow, usually from the hip bone area, is called a bone marrow transplant.
Are there different types of BMT?
Yes, there are two different types of BMT. This book focuses on allogeneic bone marrow transplant, which involves finding a donor whose tissue type closely matches yours. The donor can be related or unrelated. Related donors are usually a brother or sister. If no matching relative is found, your transplant doctor will ask the Australian Bone Marrow Donor registry to start a search (see Finding a donor, page ?). An autologous BMT uses your own blood stem cells, but this type of transplant is not discussed in this book.
If I have a common blood group, will I have a common tissue type?
No, not necessarily. There is no link between your blood type and your tissue type. Tissue type is determined by different sets of genetic proteins called human leukocyte-associated antigens (HLA), which are found on the surface of most cells. A person’s tissue type is identified by a blood test called tissue typing. Therefore, your donor can still be a bone marrow match for you but have a different blood group.
Will I need an operation to have a BMT?
No, the stem cells will simply be re-infused through your central line in the same way you receive transfusions such as platelets or red blood cells (packed cells).
What is engraftment and when will it happen?
Engraftment means new cell growth, and takes place after your bone marrow transplant when there is a sustained rise in new blood cell production. This generally occurs within 2-4 weeks after your transplant. The first obvious sign may be a rise in your white blood cell count above 0.5. This tells us that your new bone marrow cells are starting to produce new blood cells. Until this time, you are at high risk of infection and need to avoid possible sources of infection.
What are the possible side effects of a BMT?
The two main risks from the transplant process are an increase risk of infection and bleeding due to high doses of chemotherapy and/or radiation. Short-term effects may include nausea, vomiting, fatigue, mouth ulcers, weight loss, hair loss and skin reactions. Long-term effects include infertility, cataracts and possible complications in the liver, kidneys, lungs, joints and/or heart.
Allogeneic transplants carry the risk of GVHD. This occurs when the white blood cells from the donor marrow (the graft) identify the cells of the patient’s body (the host) as foreign and attack it. This can be mild in the form of skin rashes on the hands and feet, to very severe affecting liver, gut and/or lung function. (For detailed information about possible BMT complications, see page??)
What are my chances of having a successful BMT?
This is very difficult to answer as so many individual issues come into play. The outcome of your transplant is highly influenced by your original disease, the stage of your disease and your general condition at the time of the transplant. There are many other variables, including how you have responded to treatment and the closeness of the match of your donor. The best person to discuss your possible transplant outcome is your transplant doctor. He/she can discuss your individual factors that may influence your chances of success.
The basics of bone marrow transplants
The basics of bone marrow transplants

The basics of bone marrow transplants

The basics of bone marrow transplants
A bone marrow transplant (BMT) is a fairly new treatment for diseases that until recently could not be cured. Since it was first used with good results in 1968, this treatment has been used for patients with immune system diseases and blood diseases such as leukaemia, lymphoma and multiple myeloma.
In Australia each year, around 1,000 children and adults have a BMT. More than 300 people have a BMT each year in New South Wales.
What is bone marrow?
Bone marrow is the soft, spongy part in the centre of your bones where blood cells are produced. The bone marrow makes stem cells, which are early-stage cells that produce other cells. Each tissue in the body contains stem cells that renew and replace that tissue when needed due to damage or wear and tear. Stem cells generate all blood cells in the human body, including red cells, white cells and platelets.
Types of BMT
Allogeneic transplant
This type of transplant uses stem cells donated by another person (a donor) and is the focus of this book. It is called a syngeneic transplant if the donor is an identical twin.
The two types of allogeneic transplants are:
• Myeloablative or full allo: the aim is to destroy the patient’s marrow and kill the cancer cells.
• Non-myeloablative (“mini” allo): the aim is to suppress the patient’s marrow and allow the donor cells to grow and attack the cancer cells. This is the graft-versus-tumour effect.
There are two ways to collect or harvest the donor’s stem cells:
�� A peripheral blood stem cell harvest: this is used for most adult transplants and collects stem cells from the donor’s circulating blood.
�� A bone marrow harvest: this collects stem cells from the donor’s bone marrow, usually from the hip bones.
The donor’s stem cells must match the genetic make-up of your own cells as closely as possible. Blood tests, called tissue typing, are done to work out if the donor’s cells match.
The most suitable donor is usually a brother or sister whose bone marrow is a close match. There is a 25-35% chance that a patient will have a family member whose stem cells match. But if no matching relative can be found, an unrelated donor may be found in the Australasian/International Bone Marrow Donor Registry. A mismatched or autologous BMT may also be considered.
The basics of bone marrow transplants
The basics of bone marrow transplants
Autologous transplant
An autologous transplant uses your own stem cells. This type of transplant can be done if the disease is in remission or if the illness does not involve the bone marrow (eg, Hodgkin’s disease, non-Hodgkin’s lymphoma).
For an autologous BMT, stem cells are taken from the patient’s blood before the transplant, stored and then given back after high-dose chemotherapy or radiotherapy.
This book does not describe autologous BMT in detail. For more information about autologous transplants, see the BMT Network NSW publication, Autologous Bone Marrow Transplant: A Patient’s Guide.
Preparing for a BMT
The BMT team
An expert team of doctors, nurses and other support staff will care for you. The team can quickly identify and treat any problems or side effects. A good BMT program will also give patients and their families emotional and psychological support before, during and after the transplant.
For a BMT to work well, you must be healthy enough to cope with the procedure. When deciding if you should have a BMT, your doctor will consider your age, general physical condition and the type and stage of your disease.
The work up
Before a BMT, a number of tests are carried out to ensure you are healthy enough for the treatment. You will also have tests of heart, lung and kidney function before and after the BMT so your doctor can check whether these organs are still working as well after the transplant. The pre-BMT tests (also called the work up) are usually done before you are in hospital, but may be done after you are admitted.
You will need to have a dental check-up and all necessary work done before the BMT. If you or your dentist is unsure, please check with your BMT team before any work is started.
The basics of bone marrow transplants
Making informed decisions
Long-term implications
It is important to think about some of the possible long-term effects, such as infertility, and discuss them with your transplant doctor before starting a BMT. See page ?? for more information.
Gathering information
When you are considering a BMT, you will be given a lot of information about the process. Some people do in-depth research and think through every detail, while others just want enough information for the next day or stage. Some people only want to know enough to be informed, and choose not to read or listen to anything negative so they can stay motivated and focused.
A BMT is a serious and complicated procedure so it is vital you are informed and that you clearly understand what the BMT means for you. This requires good communication with your BMT doctor and the rest of the team.
At your first visits to the doctor, you will receive a lot of information about the proposed BMT, its side effects and possible complications. To help you absorb this information, it can help to take notes during the consultation or tape-record the discussion. Many people like to have a relative or friend go with them, to take part in the discussion, take notes or just listen.
If you don’t understand what you’ve been told, don’t be afraid to ask questions or to ask for the information to be repeated as often as you need. Questions are a good sign that you are working in partnership with your medical team. It is very important to be involved in your care and to express your concerns before, during and after a BMT. Your role is crucial, particularly in telling the team about how you are feeling and any symptoms you are having.
In the days before the BMT, you will need to sign a number of consent forms for the treatment or clinical trial.
Finally, remember that not everyone will want to go ahead with a BMT. After thinking about all the possible risks and benefits, some people decide it is not for them. In this case, you need to tell your doctors, and talk to them about other treatments. Your doctor will still give you the best other treatment options available.
How is a BMT done?
Collecting bone marrow stem cells
The stem cells are collected from the donor’s blood or bone marrow. If the donor is related to you, the stem cells will usually be collected from the blood. Cells from unrelated donors are harvested from the either the peripheral blood or the bone marrow, under general anaesthetic, depending on what your doctor believes is best for you and/or donor preference.
The central line
If you don’t already have one, a central venous catheter will be inserted under the skin of your chest into a vein. It is also called a central line or Hickman catheter depending on the type of line.
A central line is a long, hollow tube that usually has two or three passages (called lumens) to allow for a number of uses. It is made of silicone or hard plastic. Your central line will stay in place during the BMT and may be used to collect blood samples and to give you all the medications and fluids you need.
Your central line will usually be inserted into a large vein that runs beneath your collar bone with the tip sitting near to the entry into your heart. The rest of the central line remains outside your body for easy access. A clamp keeps the tube closed when it is not being used. The central line may be put in when you are in the operating theatre, in the x-ray department or on the ward.
Add diagram showing central line in place
Conditioning treatment
You will have several days of chemotherapy and/or radiotherapy, which destroy bone marrow and cancerous cells and make room for the healthy stem cells. This is called the conditioning or preparative regimen.
You may also hear the phrase ‘countdown to transplant’, because this treatment is expressed in your medical notes in terms of the number of days until the transplant. For example, day -5 (minus 5) means that you are five days away from the transplant day, which is called day 0. The type and number of days of chemotherapy and/or radiotherapy vary according to the disease being treated and the protocol or preferred treatment plan of the hospital where the BMT is being done.
For a myeloablative BMT, the dose of chemotherapy and/or radiotherapy given to patients during conditioning is much stronger than doses given to patients with the same disease who are not having a BMT. You may become weak, irritable and nauseous. Anti-nausea medications will help during this period. Don’t be alarmed if your blood results go down at this time, as this is what the chemotherapy or radiotherapy is supposed to do – that is, empty your bone marrow before your transplant.
The transplant
The transplant will take place a day or two after the chemotherapy and/or radiotherapy. The transplant is not a surgical procedure. It takes place in your hospital room, not an operating room.
You may be given medication before the transplant to prevent a reaction to the transplanted cells. This is more likely to occur when the match between the donor marrow and the patient is not exact or the blood groups are different.
The healthy bone marrow stem cells are infused through your central line, in much the same way that any blood product is given. Many patients describe the actual transplant as an anticlimax, as it all over so quickly – usually between 30 minutes and an hour.
You will be checked frequently for signs of fever, chills, hives and chest pains while the bone marrow is being infused. When the transplant is completed, the days and weeks of waiting begin.
The bone marrow begins to grow (engraftment)
Engraftment means new cell growth. It takes place after your bone marrow transplant when there is a sustained rise in new blood cell production. As a general guide, engraftment is said to have happened once the white blood cell count rises above 0.5 x 10 9 /L and the platelet count to above 20 x 103 /L without transfusion.
The 2-4 weeks after the transplant are the most critical. The high-dose chemotherapy and/or radiotherapy given to you during conditioning destroyed your bone marrow, crippling your immune or defence system, leaving your body with no natural defences against infection.
As you wait for the transplanted bone marrow to migrate to the cavities of the large bones, engraft and begin producing normal blood cells, you will be very susceptible to infection and excessive bleeding. You will be given multiple antibiotics and blood transfusions to help prevent and fight infection. You will also have transfusions of platelets to prevent bleeding and additional medications to prevent and control graft-versus-host disease (GVHD), which happens when the white blood cells from the donor marrow attack the cells of the patient’s body. (For detailed information of GVHD, see page?)
While many infections start from within the body, your BMT team will take a number of precautions to minimise your exposure to viruses and bacteria in your environment. These will vary from centre to centre. Visitors and hospital personnel will wash their hands with antiseptic soap and may wear protective gowns, gloves and/or masks while in your room.
Any visitors or relatives will be asked not to visit if they are unwell eg, if they have a sore throat, runny nose, a cold /flu or upset stomach. Fresh fruits, vegetables, plants and cut flowers, which often carry fungi and bacteria that pose a risk of infection, may not be allowed in your room.
When leaving the room, you may wear a mask, gown and gloves as a barrier against bacteria and virus, and also to remind others that you are susceptible to infection.
Blood samples will be taken daily to monitor engraftment and organ function. When the transplanted bone marrow engrafts and begins producing normal blood cells, you will gradually be taken off the antibiotics, and blood and platelet transfusions will generally no longer be required.
Once the bone marrow is producing a sufficient number of healthy red blood cells, white blood cells and platelets, you will be discharged from the hospital, provided no other complications have developed. BMT patients typically spend 4-8 weeks in hospital.
How you may feel physically during the transplant
A BMT is a physically, emotionally and psychologically taxing procedure for you and your family. Seek as much help as you need to cope – toughing it out on your own is not usually the best way to cope with the transplant experience.
At times, you may feel very sick and weak during the transplant. Walking, sitting up in bed for long periods of time, reading books, talking on the phone, visiting with friends or even watching TV may require more energy than you have.
Complications can develop after a bone marrow transplant such as infection, bleeding, GVHD or liver disease, which can create additional discomfort (see page?). Pain is usually controlled with medication, which may include the use of intravenous morphine or other narcotic drugs. In addition, mouth and throat sores can develop that make eating and swallowing uncomfortable and difficult. Temporary mental confusion sometimes occurs and can be frightening for the patient who may not realise it is only temporary. The medical and nursing staff will help you and your carers deal with these problems.
Dealing with emotional and psychological concerns
Being diagnosed with a life-threatening illness can be a traumatic experience. It is common to feel overwhelmed by the amount of information you receive and the need for urgent treatment. Each person feels differently and responds differently. People will find some aspects of the treatment process more stressful than others.
It is important you know that BMT is a team effort and that you are the central and most important person in this team. Understanding your treatment plan and clear communication are essential elements in maintaining your emotional and psychological well-being. People often say it is the unexpected symptom, complication and treatment that upsets or frightens them the most. A BMT already involves a degree of uncertainty. Poor communication can add unnecessary stress to this situation. Don’t hesitate to clarify any aspect of the process.
People will vary in the amount of information they want about the transplant. Some will want to speak to others who have been through a bone marrow transplant. Some will want to be well researched on all aspects of the transplant process. Others will only need to have minimal facts about their proposed treatment. Whichever category you fall into, it will be important for you to have all the information you need about your treatment before the transplant.
You may find that you feel isolated with little control over your day-to-day activity because of the precautions taken to guard against infection while your immune system is not working properly. You will be in a single room and the number of visitors you can have at one time is restricted.
Make your room your own space with your personal effects. Try to stay as independent as you can and talk to your nurses about how you can participate in your care. Lack of privacy is another common issue for people having a BMT – talk to your nurse about allocating times when you will be as undisturbed as possible.
Waiting for the transplanted stem cells to engraft, for blood counts to return to safe levels or for side effects to disappear can be very frustrating and lead to increased stress. Try to remain positive and be realistic in your goals. BMT is an individual process that cannot be predicted all of the time.
You may find that personal relationships with family and friends come under pressure during BMT. This is not uncommon. Relationships within families will change, and it is important to recognise what these changes will be. Talk to the BMT social worker if you need help.
Each family member or close friend will cope with your BMT in their own way and this may, at times, lead to misunderstandings or conflict. Just because a family member or friend is not visiting does not mean they don’t care – they may just be taking some time out as their way of coping.
Psychological discomfort, like physical discomfort, is a normal symptom of the BMT experience. Social workers and psychologists/psychiatrists are also part of your BMT team, so call on them when you need help. There is no right or wrong way to manage all the challenges and stresses that BMT throws at you. There is only the method that works for you.
Going home
Recovering from a BMT continues for some months after you leave hospital. For the first few weeks you may be too weak to do much more than sleep, sit up and walk a bit around the house. You will need to visit the hospital or clinic regularly so your BMT team can monitor your progress and administer any medications and/or blood products needed.
It will take at least six months before you will be ready to return to work or your normal daily activities. You’ll need lots of patience and determination to cope during this period. Some people find that reaching their ‘new normal’ takes longer than others.
Your new marrow is still in its infancy and is not yet able to protect you from some bacteria and viruses encountered in everyday life. The medications you will need to control GVHD only add to this. So it is important to protect yourself from potential sources of infection. Enjoy the outdoors, dine alfresco, keep sick friends and relatives away, see movies and do the shopping at quiet times. You can get back to a normal life; you just have to take a little extra care.
Life after BMT
Life after transplant can be both exhilarating and stressful. On the one hand, it is exciting to be alive after being so close to death, and many people find their quality of life has improved after transplant.
But there is always the worry that a relapse will occur. Also, innocent statements or events can sometimes conjure up unpleasant memories of the transplant experience long after recovery. It can take a long time to come to grips with these difficulties. Tell your BMT team about any difficulties you experience.
Shaded box
Frequently asked questions
What is a bone marrow transplant (BMT)?
A BMT is a standard treatment option for some people who have life-threatening blood or immune system diseases. It is the process of replacing unhealthy bone marrow cells (stem cells) with healthy bone marrow cells. The healthy bone marrow cells are re-infused intravenously after very strong chemotherapy and/or radiotherapy, which kills your unhealthy bone marrow cells. The re-infusion of healthy bone marrow cells essentially rescues you from your chemotherapy and/or radiation by enabling your bone marrow to start producing new red and white blood cells and platelets.
What is the difference between a BMT and a peripheral blood stem cell transplant?
Both transplants aim to do the same thing – replace bone marrow stem cells in a person who has had their bone marrow destroyed by large doses of chemotherapy and or radiotherapy.
Bone marrow is the spongy substance found in the hollow of bones of the hips, legs and arms. It contains stem cells (also called CD34s), which produce all circulating blood cells: red blood cells, white blood cells and platelets.
When the stem cells are collected from circulating blood, the transplant is called a peripheral blood stem cell transplant. A transplant with stem cells collected from the marrow, usually from the hip bone area, is called a bone marrow transplant.
Are there different types of BMT?
Yes, there are two different types of BMT. This book focuses on allogeneic bone marrow transplant, which involves finding a donor whose tissue type closely matches yours. The donor can be related or unrelated. Related donors are usually a brother or sister. If no matching relative is found, your transplant doctor will ask the Australian Bone Marrow Donor registry to start a search (see Finding a donor, page ?). An autologous BMT uses your own blood stem cells, but this type of transplant is not discussed in this book.
If I have a common blood group, will I have a common tissue type?
No, not necessarily. There is no link between your blood type and your tissue type. Tissue type is determined by different sets of genetic proteins called human leukocyte-associated antigens (HLA), which are found on the surface of most cells. A person’s tissue type is identified by a blood test called tissue typing. Therefore, your donor can still be a bone marrow match for you but have a different blood group.
Will I need an operation to have a BMT?
No, the stem cells will simply be re-infused through your central line in the same way you receive transfusions such as platelets or red blood cells (packed cells).
What is engraftment and when will it happen?
Engraftment means new cell growth, and takes place after your bone marrow transplant when there is a sustained rise in new blood cell production. This generally occurs within 2-4 weeks after your transplant. The first obvious sign may be a rise in your white blood cell count above 0.5. This tells us that your new bone marrow cells are starting to produce new blood cells. Until this time, you are at high risk of infection and need to avoid possible sources of infection.
What are the possible side effects of a BMT?
The two main risks from the transplant process are an increase risk of infection and bleeding due to high doses of chemotherapy and/or radiation. Short-term effects may include nausea, vomiting, fatigue, mouth ulcers, weight loss, hair loss and skin reactions. Long-term effects include infertility, cataracts and possible complications in the liver, kidneys, lungs, joints and/or heart.
Allogeneic transplants carry the risk of GVHD. This occurs when the white blood cells from the donor marrow (the graft) identify the cells of the patient’s body (the host) as foreign and attack it. This can be mild in the form of skin rashes on the hands and feet, to very severe affecting liver, gut and/or lung function. (For detailed information about possible BMT complications, see page??)
What are my chances of having a successful BMT?
This is very difficult to answer as so many individual issues come into play. The outcome of your transplant is highly influenced by your original disease, the stage of your disease and your general condition at the time of the transplant. There are many other variables, including how you have responded to treatment and the closeness of the match of your donor. The best person to discuss your possible transplant outcome is your transplant doctor. He/she can discuss your individual factors that may influence your chances of success.
The basics of bone marrow transplants
The basics of bone marrow transplants

diabetes overview
What is Diabetes?
Diabetes is a disease in which the body does not produce any or enough insulin, or is not able to use insulin effectively. Insulin is a hormone which combines with glucose (sugar) in the blood. It helps glucose or sugar to enter the body’s cells to be used for energy.
The different types of diabetes
Type 1 diabetes
Type 1 accounts for only 5-10% of people with diabetes. People with type 1 diabetes do not produce insulin. This type of diabetes usually begins in childhood or before age 30. A person with type 1 will need to take insulin daily in addition to eating well and being active.
Type 2 diabetes
Type 2 diabetes is the most common type and accounts for 90-95% of people with diabetes. In type 2 diabetes, the body does not make enough insulin or is not able to use it. This type of diabetes is most often found in people over age 45, but is becoming more common in younger people, including children.
In the early stages, people with type 2 can often maintain a normal blood glucose by healthful eating and regular activity. However, as the disease progresses, oral pills or insulin are usually needed to achieve target blood glucose goals.
Gestational diabetes
Gestational diabetes is a special type of diabetes that occurs in a small number of pregnant women. After pregnancy, blood glucose levels usually return to normal. However, a woman who has had gestational diabetes, has a greater chance of developing type 2 diabetes later in life, especially if she is overweight and sedentary.
Pre-diabetes (impaired fasting glucose)
Pre-diabetes is a condition where the fasting blood glucose is higher than normal, but not yet at the level to diagnose diabetes. A person with pre-diabetes can lower the risk of developing diabetes by losing weight, being active, and eating a healthy diet.

diabetes overview
Diabetes Care
Taking care of your diabetes will help you feel better and may help reduce or delay the problems associated with diabetes such as heart attack, stroke, blindness, kidney disease or losing a foot or leg. The management of diabetes focuses on controlling the diabetes ABCs:
• A1C (Pronounced A-one-C): A laboratory blood test that measures your average blood glucose level over
the past three months.
• Blood Pressure: High blood pressure makes your heart work too hard.
• Cholesterol: LDL or bad cholesterol builds up and clogs your arteries and HDL or good cholesterol helps remove cholesterol from your blood vessels.
You and your health care team will need to monitor your ABCs. The chart below lists recommended target numbers.
Diabetes ABCs
diabetes overview
Health care team
Working with your health care team, you can manage your diabetes to achieve your target goals. One of your team members is the pharmacist.
Our pharmacist can answer questions about diabetes products, including blood glucose meters, medications and foot care products. Another member of your health care team is a Registered Dietitian (RD), especially one with Diabetes Education Certification (CDE). Working with a dietitian, you can learn how to balance your food, activity and medication. Together you and your dietitian can develop an individualized meal plan based on your food likes and dislikes as well as your lifestyle that will help you achieve your target ABCs.
But remember, you are the leader of your diabetes care team.
Controlling diabetes
Controlling diabetes is a balance of healthful eating, regular activity and medication. Checking your blood sugar lets you know if you need to adjust any of the components.
• Blood glucose monitoring
To help control your diabetes you may need to check your own blood glucose at home with a meter. It tells you what your blood glucose is at the time you do the test. Checking at different times of the day – before
and after meals, before and after exercise, before bed - allows you to look for patterns. Most meters today read the blood sample results as plasma rather than whole blood glucose values. Make sure you know whether your meter provides plasma or whole blood results.
Goals for blood glucose control
diabetes overview

Diabetes meal planning
Eating right with diabetes is no longer about following a “diet”. It is about making healthy food choices, and the foods that are good for you are also good for everyone in your family.
• The basic principles of diabetic meal planning are:
1. Do not skip meals. Skipping meals can cause your blood glucose to drop if taking certain diabetes medications. And people who skip meals tend to overeat at the next meal which can raise your blood glucose.
2. Control carbohydrate intake. Carbohydrates in foods are what most affect blood glucose levels. That does not mean you should not eat carbohydrates, but rather, control how much is eaten at meals and snacks. Carbohydrates come from many foods:
• Starches, such as bread, rice, cereals, pasta, starchy vegetables (such as potatoes, corn and green peas), dried beans and peas.
• Natural sugars found in milk (lactose) and fruit (fructose).
• Added sugars such as table sugar, corn syrup, molasses, dextrose, honey, high fructose corn syrup, and fruit juice concentrate.
3. Eat a variety of foods. Consume the recommended number of servings from each of the food groups to ensure you get all the nutrients you need on a daily basis. See the Diabetes Food Pyramid on page 10.
4. Eat less saturated fat, trans fat and cholesterol. Saturated fat, trans fat and to a lesser extent, cholesterol in your diet may increase your blood cholesterol level, which in turn may increase your risk of heart disease.
Because there is a strong connection between diabetes and heart disease, it is important to maintain a normal blood cholesterol level.
• Saturated fats are usually solid at room temperature and found mainly in animal foods such as meat fat, poultry skin, lard, butter, cheese, and whole and 2% milk.
• Trans fats are produced when oils (unsaturated fats) are made harder through a process called hydrogenation. Trans fats are found mainly in commercial baked goods, fried foods, and stick margarines.
• Dietary cholesterol is found only in animal foods, and the most concentrated sources are egg yolks, organ meats, shrimp and squid.

5. Eat more fiber. People with diabetes need to eat more fiber just like everyone else. Many people routinely eat only about half the recommended amount of fiber per day. A diet rich in fiber fills you up and helps lower blood cholesterol levels. Fiber comes from many foods:
• Grains and grain products especially whole grain breads and cereals.
• Fruits and vegetables. Fiber is found in all fruits and vegetables including fresh, frozen, canned, and dried. Cooking does not lower the fiber content of the food, but juice has little or no fiber.
• Cooked dried peas and beans such as lima, kidney, black, pinto, and navy beans, and split peas and chick peas are very high in fiber – about 5 grams or more per 1/2 cup serving.
Slowly increase the amount of fiber you eat. Aim for 21-38 gramsper day or 14 grams per 1000 calories consumed. Be sure to consume water and other beverages throughout the day as you increase your fiber
intake. Thirst is the best indicator to drink more fluid.
6. Maintain a healthy body weight. If overweight, aim for a moderate weight loss of 5 to 10% of your current weight. This amount of weight loss can help improve your blood glucose, blood cholesterol and blood pressure.
The government classifies weight by Body Mass Index (BMI). A healthy BMI is 18.5 – 24.9. To lose weight, eat less and move more.

BMI                       Classification
<18.5                      Underweight
18.5 - 24.9                  Normal
25.0 - 29.9              Overweight
30.0 - 39.9                Obesity
>40.0                     Extreme obesity
This formula can be used to calculate your BMI

How do I set up a meal plan?
A meal plan is a guide that tells you how much and what kinds of food to eat at meals and snacks. A good meal plan should fit in with your eating habits and schedule. You and your dietitian should work together to design a meal plan that’s right for you and includes foods you enjoy.
Understanding your meal plan allows for flexibility so you can eat out, use convenience foods and allow for special events. It will also help you adjust for changes in your schedule, such as days when meals may
be delayed or when you are feeling ill.
diabetes overview
Carbohydrate counting
Carbohydrate counting is a meal planning tool that allows you to eat carbohydrates in amounts that keep your blood glucose in your target range.
A dietitian can help you determine the total amount of daily carbohydrate that is best for your sex, age, and activity level and how to distribute it through the day.
The first step: Know which foods contain carbohydrates. Carbohydrates include both starches and sugars. It is best if most of the carbohydrates you eat come from healthy foods like bread, cereals, grains, cooked dried beans and peas, starchy vegetables, fruits, milk, and yogurt. These foods contain vitamins, minerals and fiber. Sugars and sweets have little nutritional value and are often high in fat. It’s OK to eat sweets once in a while, but when you do eat sweets you must eat less of other carbohydrates, rather than just add the sweets to your meal plan.
The second step: Learn serving sizes. A serving of starch, fruit or milk is the amount of food that provides about 15 grams of carbohydrate and is referred to as 1 carbohydrate choice or serving. See the Diabetes Food Pyramid on p.10 to learn serving sizes for foods in the starch, fruit and milk groups. It will help to measure or weigh foods until you can judge them by looking at a portion on your plate.

The third step: Spread carbohydrate throughout the day. Based on the total amount of carbohydrate in your meal plan, divide your daily carbohydrate up into meals and snacks. To avoid fluctuations in your blood glucose, it is best to eat about the same amount of carbohydrate at each meal and snack and to eat meals and
snacks at about the same time each day.

How many carbohydrates choices do you need? A general guide is:
Women: 45-60 grams (3-4 choices) per meal; 0-30 grams (0-2 choices) per snack
Men: 60-75 grams (4-5 choices) per meal; 0-30 grams (0-2 choices) per snack

Checking your blood glucose levels before and after different meals will help you learn the amount of carbohydrate in meals and snacks that works for you. If you need to lose weight or are very active, you may need fewer or more servings than recommended above.

The Diabetes Food Pyramid
Another approach to meal planning is to use the Diabetes Food Pyramid (above) as a guide of what and how much to eat. This allows for a variety of foods every day and can be used by the whole family.
The Diabetes Food Pyramid groups foods by carbohydrate content so it works better for people with diabetes. It is different from the USDA My Pyramid you may have seen in government publications, pamphlets or on food packaging.

How many servings?
The number of servings needed from each food group in the Pyramid is given in ranges, rather than a single number. For example, the bottom group Grains/Beans/Starchy Vegetables suggests 6 or more servings per day. Why? Because we are very different people. Smaller people and older people need less food than larger people, younger people or very active people. Thus, a small, older woman will need fewer servings per day than a younger, large man.
Individuals may need to make adjustments according to their own needs and blood sugars. Your health care team, particularly your dietitian, may prescribe a slightly different plan for you based on your target goals.
The plate method Another meal planning method is the plate method. With this method, no measuring is required. Instead, your plate determines the correct portion. Divide a plate into quarters. For lunch or dinner, use one quarter of the plate for Meat and Meat Substitutes, one quarter for Grains, Beans & Starchy Vegetables and the remaining half for Vegetables. For breakfast, use one quarter of the plate for Meat & Meat Substitutes if desired, and one half for Grains, Beans & Starchy Vegetables. A glass of milk, or a serving of fruit may be added to any of the meals or reserved for snacks.
Too many people cover their plate with large servings of starch or protein foods and skimp on vegetables. This way of eating can lead to too many calories, too much carbohydrate and too much saturated fat.

How sweet it is
Sugar substitutes or sugar replacers include nonnutritive sweeteners and sugar alcohols. They can both replace sugar sweeteners in foods and drinks.
• Nonnutritive sweeteners – No calories or carbohydrates There are five nonnutritive sweeteners approved by the Food and Drug Administration (FDA) for use in foods and beverages:
• Acesulfame potassium (K)
• Aspartame
• Neotame
• Saccharin
• Sucralose
These nonnutritive sweeteners are calorie-free (except for aspartame which is very low in calories). Products that use these sugar substitutes include diet soft drinks, sugar-free gelatins, powdered drink mixes, chewing
gum, jellies, jams, pancake syrup and light yogurts. They are also available as tabletop sweeteners.
• Are nonnutritive sweeteners safe?
The five nonnutritive sweeteners currently on the market were extensively tested before they were approved by the FDA. They are considered safe for everyone, including children and pregnant women, in amounts that consumers would typically consume of them. However, people with phenylketonuria (PKU), a rare genetic disease, need to limit their intake of aspartame.
• Sugar alcohols (Polyols) – Contain calories and carbohydrates Sugar alcohols are carbohydrates that sweeten with fewer calories per gram than sugar. Also called polyols, sugar alcohols are neither sugars nor alcohols. Sugar alcohols include:
• Sorbitol, mannitol, xylitol, erythritol, D-tagatose
• Isomalt, lactitol, maltitol, trehalose
• Hydrogenated starch hydrolysates (HSH)
Sugar alcohols are often used in sugar-free or no-sugar-added foods such as gum, cookies, and ice cream.

Currently, there are two low-calorie sweeteners made from the sugar alcohol erythritol - ZSweet and Sun Crystals - available as tabletop sweeteners in some stores and on the internet.
• Stevia
Stevia is a calorie-free sweetener made from a plant in South America. FDA has not approved stevia for use as a nonnutritive sweetener in the United States for lack of scientific evidence to assure its safety.
However, stevia is sold as a dietary supplement, which does not require FDA approval. Check with your health professional before using it.
• How do nonnutritive sweeteners or sugar alcohols fit into your meal plan?
Nonnutritive sweeteners and sugar alcohols can help lower the amount of carbohydrate in foods and allow for more flexibility in your meal plan. However, sugar-free or no-sugar-added does not mean carbohydratefree or low-calorie. Sugar-free or no-sugar-added means that no sugar sweeteners such as white sugar, brown sugar, honey, syrup, molasses, high fructose corn syrup or fruit juice concentrate have been used in
the food or drink.
Often times, a sugar-free or no-sugar-added food has as many calories, and grams of fat and carbohydrate as the regular product. Check the Nutrition Facts label to determine how a sugar-free food or drink fits into your meal plan and/or carbohydrate budget. For example, sugar-free gum is calorie-free and carbohydrate-free, and can be consumed as a free food. In contrast, sugar-free cookies contain calories, fat and carbohydrate, and must be counted in your meal plan and/or carbohydrate budget, not eaten in addition to it.

Using the Nutrition Facts label
Serving Size: The serving size is the first thing you should look at. All the numbers in the Nutrition Facts box are based on this serving size.
If you eat more or less than this amount, you must adjust the numbers accordingly. Be aware that the serving size on the food label may not be the same as the serving size in your food plan.
% Daily Value (%DV): %DV is a useful tool for comparing foods.
If the %DV is 5% or less, it is low in that nutrient. If the %DV is
20% or more, it is high in that nutrient.
Total Fat: Look at the grams of total fat as well as the grams
of saturated fat and trans fat.
• A low fat food has 3 grams or less fat per serving.
• A low saturated fat food has 1 or less grams saturated fat per serving and no more than 15% calories from saturated fat.
• Trans fat: Try to eat as little as possible because it increases your risk of heart disease.
Sodium: Limit sodium to help reduce your risk of, or help control, high blood pressure. The recommended intake for healthy adults is 2300 mg sodium per day. For people with high blood pressure, the recommended
intake is 1500-2000 mg sodium per day.
Total Carbohydrate: Look at the grams of total carbohydrate.
It is the grams of total carbohydrate that needs to be counted intoyour meal plan, not the grams of sugar. Remember, 15 grams of carbohydrate is the same as one carbohydrate choice or serving.
The grams of sugar and fiber (and sugar alcohols if present) are indented under total carbohydrate because they are included in the total.
• If a food contains 5 or more grams of dietary fiber, you can
subtract half the fiber from the total carbohydrate grams
to get a more accurate carbohydrate count.
• If a food contains 5 or more grams of sugar alcohols,
you can subtract half the sugar alcohol content from
the total carbohydrate grams to get a more
accurate carbohydrate count.
• A free food is any food that contains less than 20 calories and less than 5 grams of carbohydrate per serving.

Shopping list
The first step to eating well is shopping right. You can find a wide selection of healthful foods at your supermarket.
At Stop & Shop, it is easy to find healthy foods. Just look for the Healthy Ideas symbol on the shelf tag! A Healthy Ideas food must meet strict criteria. A Healthy Ideas food will be low in total fat, saturated fat, and cholesterol and free of artificial trans fat. A Healthy Ideas food is also controlled in sodium and sugar and must provide at least 10% of the Daily Value for either protein, fiber, calcium, iron, vitamin A or vitamin C.
For complete criteria, visit our website, stopandshop.com or pick up a Healthy Ideas brochure at your store.
diabetes overview

Fruits and Vegetables
• All fresh, raw fruits and vegetables are healthy choices.
• Choose canned fruits in light syrup or juice.
• Choose no-salt-added canned vegetables or those with the Healthy Ideas symbol.
• Choose whole fruits over fruit juices.
• When buying juice, look for 100% juice (those with the Healthy Ideas symbol). Limit juice if overweight, because it has as many calories as regular soda.
• Choose plain frozen vegetables over those with sauce.
• Choose more dark green and deep yellow vegetables.
• To save time, buy pre-washed and pre-cut vegetables and fruits.

Meat, Poultry, Seafood and other Protein Sources
For the healthiest choices, look for the Healthy Ideas symbol. Only Extra Lean meats, with less than or equal to 5 grams total fat, 2 grams saturated fat, and 95 mg cholesterol per reference serving* qualify as a
Healthy Ideas food. Lean meats, with less than or equal to 10 grams total fat, 4 grams saturated fat and 95 mg cholesterol per reference serving* are good choices too.
• Choose cuts with the words “loin” or “round” in the name, e.g. top round or pork tenderloin.
• Choose 96% or 93% lean ground beef. Fresh ground turkey breast and 93% lean ground turkey are great choices also.
• Limit high fat meats such as ribs, corned beef, sausage or bacon.
• Buy skinless poultry parts or remove the skin before cooking.
• When buying fish and shellfish, look for fresh, plain frozen or canned in water instead of oil, for fewer calories. Skip the breaded or batter-dipped frozen fish.
• Include at least two seafood meals per week for heart health.
• Canned and dried beans (legumes) are high in fiber and good sources of protein.
• Peanut butter and other nut butters are another good alternative to animal protein. To qualify for the Healthy Ideas symbol, peanut and nut butters must be free of any added sugar.
• Choose egg substitutes for protein without fat and cholesterol.
• Look for soy products with at least 8.25 grams of protein per reference serving*.

Deli
• Look for deli meats with the Healthy Ideas symbol. These meats have less than 3 grams total fat and less than 1 gram saturated fat per serving.
• Look for lower sodium deli meats at the service deli.
• Choose roast beef, turkey, chicken and ham over bologna, salami, or pepperoni.
• Choose hot dogs with 3 grams of fat or less per serving (look for
the Healthy Ideas symbol). Chicken and turkey franks do not always have less fat than beef franks.
Breads, Cereals and Grains
• Choose breads that list whole grain or whole wheat flour as the first ingredient and contain at least 2.5 grams of fiber per serving.
• Look for whole grain cereals with at least 5 grams of fiber, and no more than 12 grams of sugar per serving.
• Choose quick oats or old fashioned oats over instant oatmeal varieties that have more sodium and sugar.
• Choose whole grain crackers. Go easy on cheese crackers, peanut butter crackers, and butter crackers.
• Choose whole grain pastas and whole grain blends.
• Choose brown rice and other whole grains such as bulgur and quinoa.
• Prepare rice and pasta mixes without added fat and salt.

Dairy
• Choose low fat and nonfat dairy products and plain or light yogurts.
• Nonfat milk meets the strict criteria of Healthy Ideas. Low fat milk (1%) has more saturated fat but is a good choice also.
• Limit 2% or whole milk and higher fat dairy products.
• Look for nonfat or light yogurt.
• Look for cheeses with no more than 3 g saturated fat.
• Look for light or diet margarine and cream cheese.
• Buy evaporated skim milk as a substitute for cream in coffee and recipes.
Convenience and Frozen Foods
• Frozen dinners with the Healthy Ideas symbol on the shelf tag are low in fat, saturated fat and cholesterol, and controlled in sodium (less than 600 mg per federal reference serving size*).
• Look for pasta sauces with the Healthy Ideas symbol. All Healthy Ideas pasta sauces are low fat, less than 480 mg sodium per refernce serving and are free from added sugars.
• Select broth or bean based soups over cream soups or Ramen-type soups.

Snacks and Sweets
Snacks and sweets are meant to be extras in your diet and eaten in moderation. Many snacks and sweets do not provide at least 10% of the Daily Value for a Healthy Ideas nutrient and therefore do not qualify for the
Healthy Ideas symbol. However, here are some tips to help you make good choices when you shop for these items.
• For low fat snacks, choose light microwave popcorn, pretzels and rice cakes.
• Look for low fat cookie choices including animal crackers, graham crackers, fig bars, ginger snaps, and vanilla wafers.
• Choose granola and cereal bars with at least 2.5 grams of fiber and no more than 1 gram of saturated fat and 0 grams of trans fat.
• Nuts are a healthy snack, but limit quantities.
• Choose nonfat puddings.
• Select low fat frozen desserts like light ice cream, frozen yogurt, sherbet, sorbet, Italian ice, popsicles, and fruit bars.
• No Sugar Added sweets such as sugar-free gelatin and popsicles can be a good choice, but always read the grams of total carbohydrate on No Sugar Added products.
Fats and Oils
• Choose soft margarines or spreads with 0 grams trans fat.
• Choose light or reduced fat salad dressings.
• Choose canola oil or olive oil for cooking.
• Choose light or reduced fat mayonnaise.

Be active each day
Physical activity is like medicine – but it costs nothing and has no negative side effects. Regular physical activity can help:
• Improve insulin sensitivity and lower blood sugars
• Achieve and maintain a healthy weight
• Improve blood pressure and blood cholesterol levels
• Relieve stress and improve emotional well-being To be physically fit, there are three things you need to work on:
aerobic endurance, muscle strengthening, and flexibility.
Aerobic endurance exercises increase breathing and heart rate, and help burn calories. Aerobic activities should be done most preferably all days of the week, for at least 30 minutes. Work hard enough to elevate
your breathing and heart rate, but not so hard you can’t carry on a conversation. Examples include brisk walking, jogging, bicycling, swimming, and rowing. An alternative to counting minutes is to get a step counter and count steps. For good health, aim for 10,000 steps daily, for weight loss aim for 12,000 – 15,000 steps daily.
Muscle strengthening exercises build muscle, maintain bones, and increase body metabolism, which helps with weight control. You can go to a gym and lift weights or use hand/ankle weights at home. Select a weight you can lift 8 times in good form before you have to stop and rest your muscles. Muscle strengthening exercises should be done 2 to 4 times per week in sets of 1 to 3 with 8 to 12 repetitions per set using arms, legs and trunk, e.g. arm lifts, leg curls and crunches/push-ups.
Flexibility (stretching) exercises help keep your body limber and reduce muscle stiffness. Stretching should be done slowly, without jerking.
Hold the stretched position for at least 10 seconds. Do 4 to 6 stretching exercises per session. Stretch after doing your endurance and muscle strengthening exercises.
diabetes overview

diabetes overview

diabetes overview
What is Diabetes?
Diabetes is a disease in which the body does not produce any or enough insulin, or is not able to use insulin effectively. Insulin is a hormone which combines with glucose (sugar) in the blood. It helps glucose or sugar to enter the body’s cells to be used for energy.
The different types of diabetes
Type 1 diabetes
Type 1 accounts for only 5-10% of people with diabetes. People with type 1 diabetes do not produce insulin. This type of diabetes usually begins in childhood or before age 30. A person with type 1 will need to take insulin daily in addition to eating well and being active.
Type 2 diabetes
Type 2 diabetes is the most common type and accounts for 90-95% of people with diabetes. In type 2 diabetes, the body does not make enough insulin or is not able to use it. This type of diabetes is most often found in people over age 45, but is becoming more common in younger people, including children.
In the early stages, people with type 2 can often maintain a normal blood glucose by healthful eating and regular activity. However, as the disease progresses, oral pills or insulin are usually needed to achieve target blood glucose goals.
Gestational diabetes
Gestational diabetes is a special type of diabetes that occurs in a small number of pregnant women. After pregnancy, blood glucose levels usually return to normal. However, a woman who has had gestational diabetes, has a greater chance of developing type 2 diabetes later in life, especially if she is overweight and sedentary.
Pre-diabetes (impaired fasting glucose)
Pre-diabetes is a condition where the fasting blood glucose is higher than normal, but not yet at the level to diagnose diabetes. A person with pre-diabetes can lower the risk of developing diabetes by losing weight, being active, and eating a healthy diet.

diabetes overview
Diabetes Care
Taking care of your diabetes will help you feel better and may help reduce or delay the problems associated with diabetes such as heart attack, stroke, blindness, kidney disease or losing a foot or leg. The management of diabetes focuses on controlling the diabetes ABCs:
• A1C (Pronounced A-one-C): A laboratory blood test that measures your average blood glucose level over
the past three months.
• Blood Pressure: High blood pressure makes your heart work too hard.
• Cholesterol: LDL or bad cholesterol builds up and clogs your arteries and HDL or good cholesterol helps remove cholesterol from your blood vessels.
You and your health care team will need to monitor your ABCs. The chart below lists recommended target numbers.
Diabetes ABCs
diabetes overview
Health care team
Working with your health care team, you can manage your diabetes to achieve your target goals. One of your team members is the pharmacist.
Our pharmacist can answer questions about diabetes products, including blood glucose meters, medications and foot care products. Another member of your health care team is a Registered Dietitian (RD), especially one with Diabetes Education Certification (CDE). Working with a dietitian, you can learn how to balance your food, activity and medication. Together you and your dietitian can develop an individualized meal plan based on your food likes and dislikes as well as your lifestyle that will help you achieve your target ABCs.
But remember, you are the leader of your diabetes care team.
Controlling diabetes
Controlling diabetes is a balance of healthful eating, regular activity and medication. Checking your blood sugar lets you know if you need to adjust any of the components.
• Blood glucose monitoring
To help control your diabetes you may need to check your own blood glucose at home with a meter. It tells you what your blood glucose is at the time you do the test. Checking at different times of the day – before
and after meals, before and after exercise, before bed - allows you to look for patterns. Most meters today read the blood sample results as plasma rather than whole blood glucose values. Make sure you know whether your meter provides plasma or whole blood results.
Goals for blood glucose control
diabetes overview

Diabetes meal planning
Eating right with diabetes is no longer about following a “diet”. It is about making healthy food choices, and the foods that are good for you are also good for everyone in your family.
• The basic principles of diabetic meal planning are:
1. Do not skip meals. Skipping meals can cause your blood glucose to drop if taking certain diabetes medications. And people who skip meals tend to overeat at the next meal which can raise your blood glucose.
2. Control carbohydrate intake. Carbohydrates in foods are what most affect blood glucose levels. That does not mean you should not eat carbohydrates, but rather, control how much is eaten at meals and snacks. Carbohydrates come from many foods:
• Starches, such as bread, rice, cereals, pasta, starchy vegetables (such as potatoes, corn and green peas), dried beans and peas.
• Natural sugars found in milk (lactose) and fruit (fructose).
• Added sugars such as table sugar, corn syrup, molasses, dextrose, honey, high fructose corn syrup, and fruit juice concentrate.
3. Eat a variety of foods. Consume the recommended number of servings from each of the food groups to ensure you get all the nutrients you need on a daily basis. See the Diabetes Food Pyramid on page 10.
4. Eat less saturated fat, trans fat and cholesterol. Saturated fat, trans fat and to a lesser extent, cholesterol in your diet may increase your blood cholesterol level, which in turn may increase your risk of heart disease.
Because there is a strong connection between diabetes and heart disease, it is important to maintain a normal blood cholesterol level.
• Saturated fats are usually solid at room temperature and found mainly in animal foods such as meat fat, poultry skin, lard, butter, cheese, and whole and 2% milk.
• Trans fats are produced when oils (unsaturated fats) are made harder through a process called hydrogenation. Trans fats are found mainly in commercial baked goods, fried foods, and stick margarines.
• Dietary cholesterol is found only in animal foods, and the most concentrated sources are egg yolks, organ meats, shrimp and squid.

5. Eat more fiber. People with diabetes need to eat more fiber just like everyone else. Many people routinely eat only about half the recommended amount of fiber per day. A diet rich in fiber fills you up and helps lower blood cholesterol levels. Fiber comes from many foods:
• Grains and grain products especially whole grain breads and cereals.
• Fruits and vegetables. Fiber is found in all fruits and vegetables including fresh, frozen, canned, and dried. Cooking does not lower the fiber content of the food, but juice has little or no fiber.
• Cooked dried peas and beans such as lima, kidney, black, pinto, and navy beans, and split peas and chick peas are very high in fiber – about 5 grams or more per 1/2 cup serving.
Slowly increase the amount of fiber you eat. Aim for 21-38 gramsper day or 14 grams per 1000 calories consumed. Be sure to consume water and other beverages throughout the day as you increase your fiber
intake. Thirst is the best indicator to drink more fluid.
6. Maintain a healthy body weight. If overweight, aim for a moderate weight loss of 5 to 10% of your current weight. This amount of weight loss can help improve your blood glucose, blood cholesterol and blood pressure.
The government classifies weight by Body Mass Index (BMI). A healthy BMI is 18.5 – 24.9. To lose weight, eat less and move more.

BMI                       Classification
<18.5                      Underweight
18.5 - 24.9                  Normal
25.0 - 29.9              Overweight
30.0 - 39.9                Obesity
>40.0                     Extreme obesity
This formula can be used to calculate your BMI

How do I set up a meal plan?
A meal plan is a guide that tells you how much and what kinds of food to eat at meals and snacks. A good meal plan should fit in with your eating habits and schedule. You and your dietitian should work together to design a meal plan that’s right for you and includes foods you enjoy.
Understanding your meal plan allows for flexibility so you can eat out, use convenience foods and allow for special events. It will also help you adjust for changes in your schedule, such as days when meals may
be delayed or when you are feeling ill.
diabetes overview
Carbohydrate counting
Carbohydrate counting is a meal planning tool that allows you to eat carbohydrates in amounts that keep your blood glucose in your target range.
A dietitian can help you determine the total amount of daily carbohydrate that is best for your sex, age, and activity level and how to distribute it through the day.
The first step: Know which foods contain carbohydrates. Carbohydrates include both starches and sugars. It is best if most of the carbohydrates you eat come from healthy foods like bread, cereals, grains, cooked dried beans and peas, starchy vegetables, fruits, milk, and yogurt. These foods contain vitamins, minerals and fiber. Sugars and sweets have little nutritional value and are often high in fat. It’s OK to eat sweets once in a while, but when you do eat sweets you must eat less of other carbohydrates, rather than just add the sweets to your meal plan.
The second step: Learn serving sizes. A serving of starch, fruit or milk is the amount of food that provides about 15 grams of carbohydrate and is referred to as 1 carbohydrate choice or serving. See the Diabetes Food Pyramid on p.10 to learn serving sizes for foods in the starch, fruit and milk groups. It will help to measure or weigh foods until you can judge them by looking at a portion on your plate.

The third step: Spread carbohydrate throughout the day. Based on the total amount of carbohydrate in your meal plan, divide your daily carbohydrate up into meals and snacks. To avoid fluctuations in your blood glucose, it is best to eat about the same amount of carbohydrate at each meal and snack and to eat meals and
snacks at about the same time each day.

How many carbohydrates choices do you need? A general guide is:
Women: 45-60 grams (3-4 choices) per meal; 0-30 grams (0-2 choices) per snack
Men: 60-75 grams (4-5 choices) per meal; 0-30 grams (0-2 choices) per snack

Checking your blood glucose levels before and after different meals will help you learn the amount of carbohydrate in meals and snacks that works for you. If you need to lose weight or are very active, you may need fewer or more servings than recommended above.

The Diabetes Food Pyramid
Another approach to meal planning is to use the Diabetes Food Pyramid (above) as a guide of what and how much to eat. This allows for a variety of foods every day and can be used by the whole family.
The Diabetes Food Pyramid groups foods by carbohydrate content so it works better for people with diabetes. It is different from the USDA My Pyramid you may have seen in government publications, pamphlets or on food packaging.

How many servings?
The number of servings needed from each food group in the Pyramid is given in ranges, rather than a single number. For example, the bottom group Grains/Beans/Starchy Vegetables suggests 6 or more servings per day. Why? Because we are very different people. Smaller people and older people need less food than larger people, younger people or very active people. Thus, a small, older woman will need fewer servings per day than a younger, large man.
Individuals may need to make adjustments according to their own needs and blood sugars. Your health care team, particularly your dietitian, may prescribe a slightly different plan for you based on your target goals.
The plate method Another meal planning method is the plate method. With this method, no measuring is required. Instead, your plate determines the correct portion. Divide a plate into quarters. For lunch or dinner, use one quarter of the plate for Meat and Meat Substitutes, one quarter for Grains, Beans & Starchy Vegetables and the remaining half for Vegetables. For breakfast, use one quarter of the plate for Meat & Meat Substitutes if desired, and one half for Grains, Beans & Starchy Vegetables. A glass of milk, or a serving of fruit may be added to any of the meals or reserved for snacks.
Too many people cover their plate with large servings of starch or protein foods and skimp on vegetables. This way of eating can lead to too many calories, too much carbohydrate and too much saturated fat.

How sweet it is
Sugar substitutes or sugar replacers include nonnutritive sweeteners and sugar alcohols. They can both replace sugar sweeteners in foods and drinks.
• Nonnutritive sweeteners – No calories or carbohydrates There are five nonnutritive sweeteners approved by the Food and Drug Administration (FDA) for use in foods and beverages:
• Acesulfame potassium (K)
• Aspartame
• Neotame
• Saccharin
• Sucralose
These nonnutritive sweeteners are calorie-free (except for aspartame which is very low in calories). Products that use these sugar substitutes include diet soft drinks, sugar-free gelatins, powdered drink mixes, chewing
gum, jellies, jams, pancake syrup and light yogurts. They are also available as tabletop sweeteners.
• Are nonnutritive sweeteners safe?
The five nonnutritive sweeteners currently on the market were extensively tested before they were approved by the FDA. They are considered safe for everyone, including children and pregnant women, in amounts that consumers would typically consume of them. However, people with phenylketonuria (PKU), a rare genetic disease, need to limit their intake of aspartame.
• Sugar alcohols (Polyols) – Contain calories and carbohydrates Sugar alcohols are carbohydrates that sweeten with fewer calories per gram than sugar. Also called polyols, sugar alcohols are neither sugars nor alcohols. Sugar alcohols include:
• Sorbitol, mannitol, xylitol, erythritol, D-tagatose
• Isomalt, lactitol, maltitol, trehalose
• Hydrogenated starch hydrolysates (HSH)
Sugar alcohols are often used in sugar-free or no-sugar-added foods such as gum, cookies, and ice cream.

Currently, there are two low-calorie sweeteners made from the sugar alcohol erythritol - ZSweet and Sun Crystals - available as tabletop sweeteners in some stores and on the internet.
• Stevia
Stevia is a calorie-free sweetener made from a plant in South America. FDA has not approved stevia for use as a nonnutritive sweetener in the United States for lack of scientific evidence to assure its safety.
However, stevia is sold as a dietary supplement, which does not require FDA approval. Check with your health professional before using it.
• How do nonnutritive sweeteners or sugar alcohols fit into your meal plan?
Nonnutritive sweeteners and sugar alcohols can help lower the amount of carbohydrate in foods and allow for more flexibility in your meal plan. However, sugar-free or no-sugar-added does not mean carbohydratefree or low-calorie. Sugar-free or no-sugar-added means that no sugar sweeteners such as white sugar, brown sugar, honey, syrup, molasses, high fructose corn syrup or fruit juice concentrate have been used in
the food or drink.
Often times, a sugar-free or no-sugar-added food has as many calories, and grams of fat and carbohydrate as the regular product. Check the Nutrition Facts label to determine how a sugar-free food or drink fits into your meal plan and/or carbohydrate budget. For example, sugar-free gum is calorie-free and carbohydrate-free, and can be consumed as a free food. In contrast, sugar-free cookies contain calories, fat and carbohydrate, and must be counted in your meal plan and/or carbohydrate budget, not eaten in addition to it.

Using the Nutrition Facts label
Serving Size: The serving size is the first thing you should look at. All the numbers in the Nutrition Facts box are based on this serving size.
If you eat more or less than this amount, you must adjust the numbers accordingly. Be aware that the serving size on the food label may not be the same as the serving size in your food plan.
% Daily Value (%DV): %DV is a useful tool for comparing foods.
If the %DV is 5% or less, it is low in that nutrient. If the %DV is
20% or more, it is high in that nutrient.
Total Fat: Look at the grams of total fat as well as the grams
of saturated fat and trans fat.
• A low fat food has 3 grams or less fat per serving.
• A low saturated fat food has 1 or less grams saturated fat per serving and no more than 15% calories from saturated fat.
• Trans fat: Try to eat as little as possible because it increases your risk of heart disease.
Sodium: Limit sodium to help reduce your risk of, or help control, high blood pressure. The recommended intake for healthy adults is 2300 mg sodium per day. For people with high blood pressure, the recommended
intake is 1500-2000 mg sodium per day.
Total Carbohydrate: Look at the grams of total carbohydrate.
It is the grams of total carbohydrate that needs to be counted intoyour meal plan, not the grams of sugar. Remember, 15 grams of carbohydrate is the same as one carbohydrate choice or serving.
The grams of sugar and fiber (and sugar alcohols if present) are indented under total carbohydrate because they are included in the total.
• If a food contains 5 or more grams of dietary fiber, you can
subtract half the fiber from the total carbohydrate grams
to get a more accurate carbohydrate count.
• If a food contains 5 or more grams of sugar alcohols,
you can subtract half the sugar alcohol content from
the total carbohydrate grams to get a more
accurate carbohydrate count.
• A free food is any food that contains less than 20 calories and less than 5 grams of carbohydrate per serving.

Shopping list
The first step to eating well is shopping right. You can find a wide selection of healthful foods at your supermarket.
At Stop & Shop, it is easy to find healthy foods. Just look for the Healthy Ideas symbol on the shelf tag! A Healthy Ideas food must meet strict criteria. A Healthy Ideas food will be low in total fat, saturated fat, and cholesterol and free of artificial trans fat. A Healthy Ideas food is also controlled in sodium and sugar and must provide at least 10% of the Daily Value for either protein, fiber, calcium, iron, vitamin A or vitamin C.
For complete criteria, visit our website, stopandshop.com or pick up a Healthy Ideas brochure at your store.
diabetes overview

Fruits and Vegetables
• All fresh, raw fruits and vegetables are healthy choices.
• Choose canned fruits in light syrup or juice.
• Choose no-salt-added canned vegetables or those with the Healthy Ideas symbol.
• Choose whole fruits over fruit juices.
• When buying juice, look for 100% juice (those with the Healthy Ideas symbol). Limit juice if overweight, because it has as many calories as regular soda.
• Choose plain frozen vegetables over those with sauce.
• Choose more dark green and deep yellow vegetables.
• To save time, buy pre-washed and pre-cut vegetables and fruits.

Meat, Poultry, Seafood and other Protein Sources
For the healthiest choices, look for the Healthy Ideas symbol. Only Extra Lean meats, with less than or equal to 5 grams total fat, 2 grams saturated fat, and 95 mg cholesterol per reference serving* qualify as a
Healthy Ideas food. Lean meats, with less than or equal to 10 grams total fat, 4 grams saturated fat and 95 mg cholesterol per reference serving* are good choices too.
• Choose cuts with the words “loin” or “round” in the name, e.g. top round or pork tenderloin.
• Choose 96% or 93% lean ground beef. Fresh ground turkey breast and 93% lean ground turkey are great choices also.
• Limit high fat meats such as ribs, corned beef, sausage or bacon.
• Buy skinless poultry parts or remove the skin before cooking.
• When buying fish and shellfish, look for fresh, plain frozen or canned in water instead of oil, for fewer calories. Skip the breaded or batter-dipped frozen fish.
• Include at least two seafood meals per week for heart health.
• Canned and dried beans (legumes) are high in fiber and good sources of protein.
• Peanut butter and other nut butters are another good alternative to animal protein. To qualify for the Healthy Ideas symbol, peanut and nut butters must be free of any added sugar.
• Choose egg substitutes for protein without fat and cholesterol.
• Look for soy products with at least 8.25 grams of protein per reference serving*.

Deli
• Look for deli meats with the Healthy Ideas symbol. These meats have less than 3 grams total fat and less than 1 gram saturated fat per serving.
• Look for lower sodium deli meats at the service deli.
• Choose roast beef, turkey, chicken and ham over bologna, salami, or pepperoni.
• Choose hot dogs with 3 grams of fat or less per serving (look for
the Healthy Ideas symbol). Chicken and turkey franks do not always have less fat than beef franks.
Breads, Cereals and Grains
• Choose breads that list whole grain or whole wheat flour as the first ingredient and contain at least 2.5 grams of fiber per serving.
• Look for whole grain cereals with at least 5 grams of fiber, and no more than 12 grams of sugar per serving.
• Choose quick oats or old fashioned oats over instant oatmeal varieties that have more sodium and sugar.
• Choose whole grain crackers. Go easy on cheese crackers, peanut butter crackers, and butter crackers.
• Choose whole grain pastas and whole grain blends.
• Choose brown rice and other whole grains such as bulgur and quinoa.
• Prepare rice and pasta mixes without added fat and salt.

Dairy
• Choose low fat and nonfat dairy products and plain or light yogurts.
• Nonfat milk meets the strict criteria of Healthy Ideas. Low fat milk (1%) has more saturated fat but is a good choice also.
• Limit 2% or whole milk and higher fat dairy products.
• Look for nonfat or light yogurt.
• Look for cheeses with no more than 3 g saturated fat.
• Look for light or diet margarine and cream cheese.
• Buy evaporated skim milk as a substitute for cream in coffee and recipes.
Convenience and Frozen Foods
• Frozen dinners with the Healthy Ideas symbol on the shelf tag are low in fat, saturated fat and cholesterol, and controlled in sodium (less than 600 mg per federal reference serving size*).
• Look for pasta sauces with the Healthy Ideas symbol. All Healthy Ideas pasta sauces are low fat, less than 480 mg sodium per refernce serving and are free from added sugars.
• Select broth or bean based soups over cream soups or Ramen-type soups.

Snacks and Sweets
Snacks and sweets are meant to be extras in your diet and eaten in moderation. Many snacks and sweets do not provide at least 10% of the Daily Value for a Healthy Ideas nutrient and therefore do not qualify for the
Healthy Ideas symbol. However, here are some tips to help you make good choices when you shop for these items.
• For low fat snacks, choose light microwave popcorn, pretzels and rice cakes.
• Look for low fat cookie choices including animal crackers, graham crackers, fig bars, ginger snaps, and vanilla wafers.
• Choose granola and cereal bars with at least 2.5 grams of fiber and no more than 1 gram of saturated fat and 0 grams of trans fat.
• Nuts are a healthy snack, but limit quantities.
• Choose nonfat puddings.
• Select low fat frozen desserts like light ice cream, frozen yogurt, sherbet, sorbet, Italian ice, popsicles, and fruit bars.
• No Sugar Added sweets such as sugar-free gelatin and popsicles can be a good choice, but always read the grams of total carbohydrate on No Sugar Added products.
Fats and Oils
• Choose soft margarines or spreads with 0 grams trans fat.
• Choose light or reduced fat salad dressings.
• Choose canola oil or olive oil for cooking.
• Choose light or reduced fat mayonnaise.

Be active each day
Physical activity is like medicine – but it costs nothing and has no negative side effects. Regular physical activity can help:
• Improve insulin sensitivity and lower blood sugars
• Achieve and maintain a healthy weight
• Improve blood pressure and blood cholesterol levels
• Relieve stress and improve emotional well-being To be physically fit, there are three things you need to work on:
aerobic endurance, muscle strengthening, and flexibility.
Aerobic endurance exercises increase breathing and heart rate, and help burn calories. Aerobic activities should be done most preferably all days of the week, for at least 30 minutes. Work hard enough to elevate
your breathing and heart rate, but not so hard you can’t carry on a conversation. Examples include brisk walking, jogging, bicycling, swimming, and rowing. An alternative to counting minutes is to get a step counter and count steps. For good health, aim for 10,000 steps daily, for weight loss aim for 12,000 – 15,000 steps daily.
Muscle strengthening exercises build muscle, maintain bones, and increase body metabolism, which helps with weight control. You can go to a gym and lift weights or use hand/ankle weights at home. Select a weight you can lift 8 times in good form before you have to stop and rest your muscles. Muscle strengthening exercises should be done 2 to 4 times per week in sets of 1 to 3 with 8 to 12 repetitions per set using arms, legs and trunk, e.g. arm lifts, leg curls and crunches/push-ups.
Flexibility (stretching) exercises help keep your body limber and reduce muscle stiffness. Stretching should be done slowly, without jerking.
Hold the stretched position for at least 10 seconds. Do 4 to 6 stretching exercises per session. Stretch after doing your endurance and muscle strengthening exercises.
diabetes overview